Polyxene Kokinos MD, a Board Certified Vascular and General Surgeon of South Bay Vascular Center and Vein Institute was recently appointed as the new medical director of the O’Connor and St. Louise Hospital’s wound care clinics. Dr. Kokinos brings over 25 years of vascular surgery experience to her new position as medical director and is recognized as a national expert in the treatment of peripheral vascular and arterial disease. Dr. Kokinos has a special interest in the treatment of lower extremity and deep venous disease and is recognized as one of the country’s leading experts in this area. Working in partnership with the award winning Wound Care Center at O’Connor hospital, Dr. Kokinos was selected as the new medical director because of her cutting edge work in peripheral revascularication and ability to bring blood back into the lower leg and foot. Building upon the exceptional wound care services already in place at the O’Connor wound care center Dr. Kokinos will focus on providing state of the art minimally invasive (outpatient) procedures as the next breakthrough in wound care treatment.

Dr. Kokinos and her Partner Dr. Carlos Pineda, both board certified vascular surgeons are recognized as two of the leading wound care doctors in San Jose, Silicon Valley and all of Northern California. While podiatrists have always been the traditional starting point for the evaluation of and treatment of non-healing leg wounds, it is only the Vascular Surgeon who is fellowship trained to be able to evaluate and to treat the underlying cause of most non-healing wounds: poor circulation. Unfortunately, in many instances skin supplements, hyperbaric chambers and wound debridement are not enough to correct the underlying circulatory issues responsible for non-healing leg, foot and ankle wounds.

Dr. Kokinos is honored to be selected as the medical director at the O’Connor and St Louis Wound Care clinic’s and is excited to bring patients the most recent advances in wound care treatment to help keep Silicon Valley’s best wound care clinics at the forefront of patient care.


KPIX- TV CBS Channel 5 will feature South Bay Vascular Center and Vein Institute as a Vascular Surgery Center of Excellence on Saturday October 21, 2017 at 7:00 PM.

Recognized as the premiere Vascular Surgery practice in the greater San Francisco Bay Area, Dr. Polyxene Kokinos and Dr. Carlos Pineda will discuss their cutting edge approach for preventing lower limb amputations. Additionally, the program will focus on advanced surgical techniques to re-establish blood flow to aid in diabetic wound healing and the resolution of asymmetrical leg swelling.

Produced by Medical Media Group, South Bay Vascular Center is honored to be featured in this special presentation.

Please join us by watching KPIX -TV Channel 5 on October 21st at 7:00 PM.


Over the past 15 years the interventional treatment for peripheral arterial disease (PAD) has changed significantly with endovascular revascularization replacing surgically invasive procedures as the dominant intervention. Early detection and treatment are important to control the disease and to allow patients a full selection of treatment options.

Many types of health care providers can diagnose and treat PAD. Family physicians, internists, physician assistants, nurse practitioners and vascular specialists can all diagnose PAD by examining a patient’s medical and family history, performing a physical exam, and conducting diagnostic tests. PAD can be diagnosed through a variety of diagnostic procedures including:

  • Ankle-brachial index (ABI):A common test used to measures the difference between blood pressure at the arm and at the ankle. A difference in the two areas indicates restricted blood flow.
  • Ultrasound
  • CT and MR angiograms
  • Angiography
  • Blood tests

There are multiple options for treatment of PAD, ranging from medical interventions, surgical revascularization, and endovascular therapy. Vascular Surgeons are uniquely qualified and trained to treat patients diagnosed with PAD. Approaches to treatment include:

  • Minimally invasive endovascular procedures
  • Medical management
  • Exercise and lifestyle modifications
  • Surgical bypass Amputation

South Bay Vascular Center and Vein Institute is the recognized as the regional treatment center for the treatment and care of patients suffering from Peripheral Arterial Disease. Dr.’s Kokinos and Pineda specialized training and state of the art interventional facility offers patients a unique alternative to a hospital setting and provides the highest level of care for the treatment of PAD as an alternative to limb amputation.

If you or a loved ones suffers from PAD, call our office today at 408-376-3626 to schedule a visit.

We offer hope when others say there is none.



According to the U.S. Centers for Disease Control and Prevention (CDC), approximately 18 million people in the United States suffer from Peripheral Artery Disease (PAD), a common circulatory problem in which narrowed arteries reduce blood flow to the limbs. Estimates suggest that anywhere from 12 to 20 percent of individuals over the age of 60 are living with PAD. Approximately 160,000 to 180,000 of the estimated 18 million Americans with PAD will undergo a limb amputation as result of PAD-related condition this year, resulting in lower quality of life, high medical costs, and shorter life expectancy.

But even with these alarming numbers, general population awareness of PAD is estimated at only 25 percent. Symptoms of severe PAD include leg pain, wounds on the toes or feet, gangrene and a loss of leg mass compared to the rest of the body. Individuals are at greatest risk for PAD if you have high cholesterol, high blood pressure, or diabetes. African American and Hispanic populations are also at higher risk as are individuals with a history of smoking. Improvements in technology have allowed for the migration of interventional services from hospitals to same-day interventions at a physician’s office, which offers a more cost-efficient and patient-preferred alternative to inpatient care.

It is crucial for patients to have access to PAD screenings in the community setting to ensure the appropriate treatments are performed before undergoing an amputation. South Bay Vascular Center and Vein Institute is the leading center for the treatment of PAD in San Jose, Santa Clara County, and Silicon Valley.

If you or a loved one is facing a possible lower limb amputation, call our office to schedule a secondary consultation before agreeing to an amputation.

We offer hope when others say there is none.




What is Peripheral Arterial Disease?
Peripheral artery disease (PAD), also known as claudication, poor circulation, vascular disease, or hardening of arteries, is a chronic, life-threatening circulatory condition. PAD causes narrowing or blockage of the vessels that carry blood from the heart to the legs. The primary cause of PAD is atherosclerosis, or the buildup of plaque in the arteries. This occurs when arterial inflammation, cholesterol, calcium and scar tissue build up, forming plaque that clogs the arteries and slows blood flow to the legs. The more plaque that builds up on the inside walls of the blood vessels carrying blood from the heart to legs and arms, the more the arteries lose flexibility and narrow, putting patients at greater risk.
Risk factors for PAD
High blood pressure
High cholesterol
60+ years old.
PAD patients are at high risk of developing critical limb ischemia (CLI), a chronic condition that results in severe pain in the feet or toes, even while resting. Complications of poor circulation can include sores and wounds that won’t heal in the legs and feet. Left untreated, the complications of CLI could result in amputation of the affected limb. PAD patients are also at greater risk for heart attack and stroke. Studies have found that the total annual US costs for patients with PAD exceed $21 billion, including nearly $10 billion for hospitalizations. In Medicare alone, one study estimated spending on PAD accounted for more than 2% of all Medicare spending. PAD has been identified by the Institute of Medicine (IOM) as a priority area for comparative effectiveness research. One study suggested that endovascular therapy appears to be the least costly option in the short-run for patients with PAD.
Symptoms Blockages can restrict blood flow to the muscles, causing muscle cramps, tightness or weakness, especially during activity. In the early stages of PAD, patients may not experience any symptoms. If PAD is not treated, though, blockages may continue to grow and restrict, or even completely block, blood flow.
Common symptoms include:
Leg pain when walking
Muscle pain or cramping in legs and calf triggered by activity
Leg numbness or weakness
Coldness on lower leg or foot
Sores on toes, legs or feet that won’t heal
Change in color of legs